MCP1 polyclonal, anti-human

Quantity: 100 µg

Background:
Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.

Description:
Rabbit IgG polyclonal antibody for C-C motif chemokine 2 (CCL2) detection. Tested with WB, ELISA in Human.

Synonyms:
C-C motif chemokine 2 antibody, CCL 2 antibody, CCL2 antibody, CCL2_HUMAN antibody, Chemokine (C C motif) ligand 2 antibody, Chemokine C C motif ligand 2 antibody, Chemokine CC Motif Ligand 2 antibody, GDCF 2 antibody, GDCF 2 HC11 antibody, GDCF-2 antibody, GDCF2 antibody, HC11 antibody, HSMCR30 antibody, HSMCR30 antibody, JE antibody, MCAF antibody, MCP 1 antibody, MCP-1 antibody, MCP1 antibody, MGC9434 antibody, Monocyte chemoattractant protein 1 antibody, Monocyte chemotactic and activating factor antibody, Monocyte chemotactic and activating factor antibody, Monocyte chemotactic protein 1 antibody, Monocyte secretory protein JE antibody, SCYA2 antibody, Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody, Small inducible cytokine A2 antibody, Small inducible cytokine subfamily A (Cys Cys), member 2 antibody, Small inducible cytokine subfamily A Cys Cys member 2 antibody, Small-inducible cytokine A2 antibody, SMC CF antibody, SMC-CF antibody, SMCCF antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived human MCP1 recombinant protein (Position: Q24-T99). Human MCP1 shares 60.9% and 59.4% amino acid (aa) sequence identity with mouse and rat MCP1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.