MCP3 polyclonal, anti-mouse

Quantity: 100 µg

Background:
Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Description:
Rabbit IgG polyclonal antibody for C-C motif chemokine 7 (CCL7) detection. Tested with WB, ELISA in Mouse.

Synonyms:
C-C motif chemokine 7 antibody, CCL7 antibody, CCL7_HUMAN antibody, Chemokine CC Motif Ligand 7 antibody, FIC antibody, MARC antibody, MCP-3 antibody, MCP3 antibody, Monocyte chemoattractant protein 3 antibody, Monocyte chemotactic protein 3 antibody, NC28 antibody, RP23-350G1.4 antibody, SCYA6 antibody, SCYA7 antibody, Small inducible cytokine A7 antibody, Small-inducible cytokine A7 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.