MCPH1 Polyclonal Antibody

Background:
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
BRCT repeat inhibitor of TERT expression 1, BRIT 1, FLJ12847, Hypothetical protein FLJ12847, MCPH 1, MCPH1, MCPH1, MCT, Microcephalin 1, Microcephalin, Microcephaly primary autosomal recessive 1

Immunogen: Fusion protein of human MCPH1

Swissprot: Q8NEM0
Gene Accession: BC030702

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.