MCSF polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Description:
Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1 (CSF1) detection. Tested with IHC-P, ELISA in Mouse, Rat.

Synonyms:
Colony stimulating factor 1 (macrophage) antibody, Colony stimulating factor 1 antibody, Colony stimulating factor macrophage specific antibody, CSF 1 antibody, CSF-1 antibody, CSF1 antibody, CSF1_HUMAN antibody, Csfm antibody, Lanimostim antibody, M CSF antibody, M-CSF antibody, Macrophage Colony Stimulating Factor 1 antibody, Macrophage colony stimulating factor antibody, MCSF antibody, MGC31930 antibody, Processed macrophage colony-stimulating factor 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: IHC-P, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.