MD2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6351a
Background:
MD2 cooperates with toll-like receptor 4 (TLR4)on the cell surface in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. This protein enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
Other Names:
Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2, LY96, ESOP1, MD2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6351a was selected from the N-term region of human MD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LY96
Gene ID: 23643
Primary Accession: Q9Y6Y9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MD2 cooperates with toll-like receptor 4 (TLR4)on the cell surface in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. This protein enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
Other Names:
Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2, LY96, ESOP1, MD2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6351a was selected from the N-term region of human MD2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LY96
Gene ID: 23643
Primary Accession: Q9Y6Y9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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