MDFI antibody (clone 3B4), anti-human
€435.00
In stock
SKU
AC-AT2824a
Catalog Number: AC-AT2824a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF
Request Information AC-AT2824a">Request Information
Background:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Other Names:
MyoD family inhibitor, Myogenic repressor I-mf, MDFI
Antigen Type:
Recombinant Protein
Gene Name: MDFI
Gene ID: 4188
NCBI Accession: NP_005577.1
Primary Accession: Q99750
Other Accession: NM_005586
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Other Names:
MyoD family inhibitor, Myogenic repressor I-mf, MDFI
Antigen Type:
Recombinant Protein
Gene Name: MDFI
Gene ID: 4188
NCBI Accession: NP_005577.1
Primary Accession: Q99750
Other Accession: NM_005586
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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