MDFI (P134) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3882
Background:
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
Alternative Name:
MyoD family inhibitor, Myogenic repressor I-mf, MDFI
Application Dilution: WB: 1:500~1:1000
Specificity: MDFI (P134) polyclonal antibody detects endogenous levels of MDFI protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 100-146 of Human MDFI.
MW: ~ 25 kDa
Swis Prot.: Q99750
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
Alternative Name:
MyoD family inhibitor, Myogenic repressor I-mf, MDFI
Application Dilution: WB: 1:500~1:1000
Specificity: MDFI (P134) polyclonal antibody detects endogenous levels of MDFI protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 100-146 of Human MDFI.
MW: ~ 25 kDa
Swis Prot.: Q99750
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review