MDFI Polyclonal Antibody

Background:
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Research Area: Epigenetics and Nuclear Signaling, Developmental Biology

Synonyms:
MDFI, I-MF, I-mfa

Immunogen: Recombinant fusion protein of human MDFI (NP_005577.1).

Swissprot: Q99750
Gene ID: 4188

Calculated MW: 25 kDa
Observed MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.