MDH1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60457
Background:
Cytosolic malate dehydrogenase (MDHC or cMDH) is an important NAD-dependent enzyme involved in glycometabolism that catalyzes the formation of oxaloacetate and NADH from L-malate and NAD. MDHC is highly expressed in brain, heart and skeletal muscle and plays a role in aerobic energy production for muscle contraction, transmission of neuronal signals, absorption/ resorption pathways, collagen-supporting functions, dead cell phagocytosis, as well as pathways involved in gas exchange and cell division. Furthermore, MDHC is a regulatory subunit of the nucleic acid-conducting channel (NACh). MDHC functions as a homodimer and is highly conserved in plants, animals and bacteria. The activity of MDHC is controlled by the sesquiterpenoid juvenile hormone (JH) and the steroid hormone ecdysone.
Alternative Name:
Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, MDHA, MDHC, cMDH
Application Dilution: WB: 1:500~1:1000
Specificity: MDH1 polyclonal antibody detects endogenous levels of MDH1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MDH1.
MW: ~ 36 kDa
Swis Prot.: P40925
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cytosolic malate dehydrogenase (MDHC or cMDH) is an important NAD-dependent enzyme involved in glycometabolism that catalyzes the formation of oxaloacetate and NADH from L-malate and NAD. MDHC is highly expressed in brain, heart and skeletal muscle and plays a role in aerobic energy production for muscle contraction, transmission of neuronal signals, absorption/ resorption pathways, collagen-supporting functions, dead cell phagocytosis, as well as pathways involved in gas exchange and cell division. Furthermore, MDHC is a regulatory subunit of the nucleic acid-conducting channel (NACh). MDHC functions as a homodimer and is highly conserved in plants, animals and bacteria. The activity of MDHC is controlled by the sesquiterpenoid juvenile hormone (JH) and the steroid hormone ecdysone.
Alternative Name:
Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, Diiodophenylpyruvate reductase, MDHA, MDHC, cMDH
Application Dilution: WB: 1:500~1:1000
Specificity: MDH1 polyclonal antibody detects endogenous levels of MDH1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MDH1.
MW: ~ 36 kDa
Swis Prot.: P40925
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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