MDM2 (clone 4A8D12), anti-
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In stock
SKU
BT-MCA4700
Catalog Number: BT-MCA4700
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity:
Application(s): FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity:
Application(s): FCM
Datasheet
Request Information
Background:
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Research Area: Cell Biology
Synonyms: HDMX, LSKB, hdm2, ACTFS
Immunogen: Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Research Area: Cell Biology
Synonyms: HDMX, LSKB, hdm2, ACTFS
Immunogen: Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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