MDM2 (clone 5A10A9), anti-human
€0.00
In stock
SKU
BT-MCA2537
Catalog Number: BT-MCA2537
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human
Application(s): FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human
Application(s): FCM
Datasheet
Request Information
Background:
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Research Area: Cell Biology
Synonyms: DMX, hdm2, ACTFS
Immunogen: Synthesized peptide of human MDM2 (AA: ASEQETLVRPKPLLc).
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Research Area: Cell Biology
Synonyms: DMX, hdm2, ACTFS
Immunogen: Synthesized peptide of human MDM2 (AA: ASEQETLVRPKPLLc).
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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