MDM4 (clone 2D10F4), anti-human

MDM4 (clone 2D10F4), anti-human

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In stock
SKU
BT-MCA3238
Catalog Number: BT-MCA3238
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): IHC, ICC
Datasheet
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Background:
MDM4, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2.

Research Area: Cell Biology

Synonyms: HDMX, MDMX, MRP1, MDM4

Immunogen: Purified recombinant fragment of human MDM4 expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide.

Storage:
4°C|-20°C for long term storage
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