MDM4 N-terminal region polyclonal, anti-human, rabbit, pig, horse, bovine, dog

Background:
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Other Names:
Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4, MDM4, MDMX

Immunogen:
The immunogen for anti-MDM4 antibody: synthetic peptide directed towards the N terminal of human MDM4

Gene Name:
MDM4
Gene Name:
4194
NCBI Accession:
NP_002384
Primary Accession: O15151
Other Accession: NM_002393;NP_002384
Purification: Protein A purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.