MDM4 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP13861c
Catalog Number: AC-AP13861c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33903
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33903
Applications: WB
Datasheet
Request Information
Background:
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene.
Other Names:
Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4, MDM4, MDMX
Target/Specificity:
This MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human MDM4.
Antigen Region:
128-157
Antigen Type: Synthetic Peptide
Gene Name: MDM4
Gene ID: 4194
Primary Accession: O15151
NCBI Accession: NP_001191100.1;NP_001191101.1;NP_001265445.1;NP_001265446.1;NP_001265447.1;NP_001265448.1;NP_002384.2
Other Accession: NP_002384.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene.
Other Names:
Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4, MDM4, MDMX
Target/Specificity:
This MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human MDM4.
Antigen Region:
128-157
Antigen Type: Synthetic Peptide
Gene Name: MDM4
Gene ID: 4194
Primary Accession: O15151
NCBI Accession: NP_001191100.1;NP_001191101.1;NP_001265445.1;NP_001265446.1;NP_001265447.1;NP_001265448.1;NP_002384.2
Other Accession: NP_002384.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review