Me2-H3(K9) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP1051b
Background:
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. This protein is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Other Names:
Histone H33C, Histone H35, H3F3C
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1051b was selected from the 2Me region of human Methyl-H3-mK9(2Me). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H3-5 (HGNC:33164)
Gene ID: 440093
Primary Accession: Q6NXT2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. This protein is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Other Names:
Histone H33C, Histone H35, H3F3C
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1051b was selected from the 2Me region of human Methyl-H3-mK9(2Me). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H3-5 (HGNC:33164)
Gene ID: 440093
Primary Accession: Q6NXT2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review