Me2-H4(K20) Antibody Blocking peptide
€363.00
In stock
SKU
AC-BP3674a
Background:
Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.
Other Names:
Histone H4, HIST1H4A, H4/A, H4FA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3674a was selected from the Methyl region of human hH4-K20 (Methyl 2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H4C1
Gene ID: 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370
Primary Accession: P62805
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones.
Other Names:
Histone H4, HIST1H4A, H4/A, H4FA
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP3674a was selected from the Methyl region of human hH4-K20 (Methyl 2). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: H4C1
Gene ID: 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370
Primary Accession: P62805
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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