GDF-9 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73484
Background:
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Other Names:
GDF9; Growth/differentiation factor 9; GDF-9
Antigen Type: synthetic peptide
Antigen Type: GDF9
Gene ID: 2661
Primary Accession: O60383
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Other Names:
GDF9; Growth/differentiation factor 9; GDF-9
Antigen Type: synthetic peptide
Antigen Type: GDF9
Gene ID: 2661
Primary Accession: O60383
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