ME3 rabbit polyclonal, anti-human, mouse

Backgroud: Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008],catalytic activity:(S)-malate + NADP(+) = pyruvate + CO(2) + NADPH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,similarity:Belongs to the malic enzymes family.,tissue specificity:Expressed predominantly in organs with a low-division rate.,

Synonyms: ME3, NADP-dependent malic enzyme, mitochondrial, NADP-ME, Malic enzyme 3

Gene Name: ME3

Gene ID: 10873

SwissProt ID: Q16798

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.