MECOM polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

Synonyms: EVI1, MDS1, KMT8E, PRDM3, RUSAT2, MDS1-EVI1, AML1-EVI-1

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human MECOM

Gene Symbol: MECOM

Gene ID: 2122

Swiss prot: Q03112

Calculated MW: 118kDa

Recommended dilution:
WB 1:200-1000, IHC 1:30-150,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.