MED12 Polyclonal Antibody

Background:
The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along witHuman, MouseED13, CDK8 kinase, and cyclin C.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
Activator recruited cofactor 240 kDa component, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45, CAGH45, HOPA, KIAA0192, MED12, MED12, Mediator complex subunit 12, Mediator of RNA polymerase II transcription subunit 12, OPA containing protein, OPA-containing protein, Thyroid hormone receptor associated protein complex 230 kDa component, Thyroid hormone receptor-associated protein complex 230 kDa component, TNRC11, Trap230, Trinucleotide repeat containing gene 11 protein, Trinucleotide repeat-containing gene 11 protein

Immunogen: Synthetic peptide of human MED12

Swissprot: Q93074
Gene Accession: NP_005111

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-5372/sc-5374/sc-5375