MED15 Picoband™ (clone 6F4), anti-human

Description: Anti-MED15 Antibody Picoband™ (monoclonal, 6F4) . Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.Protein Name: Mediator of RNA polymerase II transcription subunit 15

Protein Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway.

Other Names: Mediator of RNA polymerase II transcription subunit 15, Activator-recruited cofactor 105 kDa component, ARC105, CTG repeat protein 7a, Mediator complex subunit 15, Positive cofactor 2 glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, TPA-inducible gene 1 protein, TIG-1, Trinucleotide repeat-containing gene 7 protein, MED15, ARC105, CTG7A, PCQAP, TIG1, TNRC7

Clone Name(s):
Clone: 6F4

Subcellular Localization: Nucleus. Cytoplasm.

Gene ID: 51586

Immunogen: E. coli-derived human MED15 recombinant protein (Position: M1-A285).

Calculated MW: 86753

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.