Nesprin-3 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP71222
Background:
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Other Names:
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Antigen Type: synthetic peptide
Antigen Type: SYNE3 (HGNC:19861)
Gene ID: 161176
Primary Accession: Q6ZMZ3
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.
Other Names:
SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Antigen Type: synthetic peptide
Antigen Type: SYNE3 (HGNC:19861)
Gene ID: 161176
Primary Accession: Q6ZMZ3
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