MEF2A polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
MEF2A(myocyte enhancer factor 2A) also known as RSRFC4, RSRFC9,is a protein that in humans is encoded by the MEF2A gene. MEF2A is a transcription factor in the Mef2 family. Several alternative splice variants of MEF2A were identified that were predicted to encode different protein products. Using immunofluorescence, MEF2A protein was detected in the nuclei of skeletal and cardiac muscle cells. The MEF2A gene is mapped on 15q26.3. MEF2A may be involved in induction of muscle differentiation and MEF2C in maintenance of the differentiated state. Coimmunoprecipitation assays indicated that GEF bound both MEF2A and MEF2D in vitro, and MEF2D interfered with the transcriptional activation promoted by the cooperative interaction of MEF2A and GEF. A transcriptional repressor form of MEF2A that is sumoylated at lys403 promoted dendritic claw differentiation.

Description:
Rabbit IgG polyclonal antibody for Myocyte-specific enhancer factor 2A (MEF2A) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
ADCAD1 antibody, MADS box transcription enhancer factor 2 polypeptide A antibody, MADS box transcription enhancer factor 2, polypeptide A(myocyte enhancer factor 2A) antibody, MEF 2A antibody, MEF2 antibody, MEF2A antibody, MEF2A_HUMAN antibody, Myocyte enhancer factor 2A antibody, Myocyte-specific enhancer factor 2A antibody, RSRFC4 antibody, RSRFC9 antibody, Serum response factor like protein 1 antibody, Serum response factor-like protein 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MEF2A(358-374aa MLSLGQVSAWQQHHLGQ), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human MEF2A(358-374aa MLSLGQVSAWQQHHLGQ), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.