MEF2D Polyclonal Antibody

Background:
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
MEF2D (Myocyte Enhancer Factor 2D) is a Protein Coding gene. Among its related pathways are Phospholipase-C Pathway and Development Angiotensin activation of ERK. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is MEF2A.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
DKFZp686I1536, MADS box transcription factor 2 polypeptide D, Mef2d, MEF2D, Myocyte enhancer factor 2D, Myocyte specific enhancer factor 2, polypeptide D, Myocyte specific enhancer factor 2D, Myocyte-specific enhancer factor 2D

Immunogen: Synthetic peptide of human MEF2D

Swissprot: Q14814
Gene Accession: NP005911

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:35-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.