MEF2D Polyclonal Antibody

Background:
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
MEF2D

Immunogen: Recombinant fusion protein of human MEF2D (NP_005911.1).

Swissprot: Q14814
Gene ID: 4209

Calculated MW: 49 kDa/50 kDa/55 kDa/56 kDa
Observed MW: 54 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.