Mek1/2 polyclonal, anti-human, mouse, rat antibody

Background:
MAP kinase kinase 1 (Mek1), also known as mitogen activated protein kinase kinase, MAP kinase kinase, ERK kinase 1 or microtubule-associated protein 2 kinase, is a 43 kDa dual-specificity protein kinase that phosphorylates threonine and tyrosine residues on MAP kinases such as Erk 1 and 2. Mek1 and Mek2 are involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis. Mek1 and Mek2 are activated by phosphorylation on serine 218 and 222 by serine-threonine kinase, Raf-1, which is part of the p21ras signal transduction pathway.

Other Names:
MAPK , Erk, Dual specificity mitogen-activated protein kinase kinase 1/2, MAP kinase kinase 1/2, MAPKK 1/2, ERK activator kinase 1/2, MAPK/ERK kinase 1/2, MEK 1/2

Primary Accession: Q02750.2

Other Accession: NP_002746.1

Concentration (mg/ml): 0.5 mg/ml