MEK1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Synonyms: MEK1, MKK1, MAPKK1, PRKMK1

Cellular Location: Cytoplasm,Nucleus

Immunogen:
A synthetic peptide of human MAP2K1

Gene Symbol: MAP2K1

Gene ID: 5604

Swiss prot: Q02750

Calculated MW: 43 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.