MEK1 polyclonal (Center S217/221), anti-human, mouse, rat

MEK1 polyclonal (Center S217/221), anti-human, mouse, rat

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In stock
SKU
AC-AP18703c
Catalog Number: AC-AP18703c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39686
Applications: IHC-P-Leica, WB
Datasheet

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Background:
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Other Names:
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K1, MEK1, PRKMK1

Target/Specificity:
This MEK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the Central region of human MEK1.

Antigen Region:
200-227

Antigen Type: Synthetic Peptide

Gene Name: MAP2K1 (HGNC:6840)
Gene ID: 5604
Primary Accession: Q02750
NCBI Accession: NP_002746.1
Other Accession: P36506; Q63932; P36507; Q90891; Q05116; Q01986; P29678; P31938; Q63980; Q10664; Q24324; NP_002746.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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