MEK5 (Ser311/Thr315) polyclonal, anti-human, mouse, rat, bovine, dog, chicken, monkey, Xenopus, zebrafish
€536.00
In stock
SKU
252557
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Signal Transduction, Cell Communication, Nervous and Sensory Systems
Description:
Dual specificity mitogen-activated protein kinase kinase 5 (MEK5) acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway plays a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation.
Alternate Names: MAPKK1, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK1, MAP2K1, PRKMK3
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: Q62862
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser311/Thr315 of rat MEK5.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signal Transduction, Cell Communication, Nervous and Sensory Systems
Description:
Dual specificity mitogen-activated protein kinase kinase 5 (MEK5) acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway plays a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis. Dual phosphorylation of Ser311 and Thr315 have been implicated in cell proliferation.
Alternate Names: MAPKK1, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK1, MAP2K1, PRKMK3
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: Q62862
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser311/Thr315 of rat MEK5.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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