MEKK6 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7912a
Background:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
Other Names:
Mitogen-activated protein kinase kinase kinase 6, Apoptosis signal-regulating kinase 2, MAP3K6, ASK2, MAPKKK6, MEKK6
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7912a was selected from the C-term region of human MEKK6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAP3K6
Gene ID: 9064
Primary Accession: O95382
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
Other Names:
Mitogen-activated protein kinase kinase kinase 6, Apoptosis signal-regulating kinase 2, MAP3K6, ASK2, MAPKKK6, MEKK6
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7912a was selected from the C-term region of human MEKK6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MAP3K6
Gene ID: 9064
Primary Accession: O95382
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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