MEKK6 polyclonal (C-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP7912a
Catalog Number: AC-AP7912a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0946
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB0946
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
Other Names:
Mitogen-activated protein kinase kinase kinase 6, Apoptosis signal-regulating kinase 2, MAP3K6, ASK2, MAPKKK6, MEKK6
Target/Specificity:
This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.
Antigen Region:
1028-1058
Antigen Type: Synthetic Peptide
Gene Name: MAP3K6
Gene ID: 9064
Primary Accession: O95382
NCBI Accession: NP_004663.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
Other Names:
Mitogen-activated protein kinase kinase kinase 6, Apoptosis signal-regulating kinase 2, MAP3K6, ASK2, MAPKKK6, MEKK6
Target/Specificity:
This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.
Antigen Region:
1028-1058
Antigen Type: Synthetic Peptide
Gene Name: MAP3K6
Gene ID: 9064
Primary Accession: O95382
NCBI Accession: NP_004663.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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