Meltrin Alpha human active recombinant protein

Protein Family: Peptidases, CAM Ligands

Pathway and Disease: Cell Growth and Death

Alternate Names: A Disintegrin and Metalloproteinase Domain 12 S Isoform, Meltrin-alpha, ADAM12, ADAM 12, Meltrin alphaDescription:
A Disintegrin and Metalloproteinase Domain 12 S Isoform (Meltrin alpha, ADAM12S) is involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Meltrin alpha is also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. Recombinant ADAM12S comprises a 531 amino acid fragment (208-738) corresponding to the mature ADAM12S protein isoform and is expressed in E. coli with an amino-terminal hexahistidine tag.

Source: E. coli

Applications: E, WB

Accession No.: O43184

MW: 62.16 kDa

Sequence:
His-Tag sequence not included: ETLKATKYVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRPLNIRIVLVGVEVWNDMDKCSVSQDPFTSLHEFLDWRKMKLLPRKSHDNAQLVSGVYFQGTTIGMAPIMSMCTADQSGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESFGGQKCGNRFVEEGEECDCGEPEECMNRCCNATTCTLKPDAVCAHGLCCEDCQLKPAGTACRDSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHEQQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQCQGGASRPVIGTNAVSIETNIPLQQGGRILCRGTHVYLGDDMPDPGLVLAGTKCADGKICLNRQCQNISVFGVHECAMQCHGRGVCNNRKNCHCEAHWAPPFCDKFGFGGSTDSGPIRQAEARQEAAESNRERGQGQEPVGSQEHASTASLTLI

Purity:
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.

Format:
Each vial contains 0.01 mg protein (liquid) in PBS pH7.4, 50% glycerol. Final concentration 0.1-1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment.