MEN1 (clone 7D3E10), anti-human

Background:
This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: MEAI, SCG2

Immunogen: Purified recombinant fragment of human MEN1 (AA: 392-554) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage