MERTK Polyclonal Antibody

Background:
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Research Area: Cancer, Neuroscience, Signal Transduction

Synonyms:
MERTK, MER, RP38, Tyro12, c-Eyk, c-mer

Immunogen: Recombinant fusion protein of human MERTK (NP_006334.2).

Swissprot: Q12866
Gene ID: 10461

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.