Mesothelin polyclonal, anti-human

Quantity: 100 µg

Background:
Mesothelin, also known as MSLN or MPF is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

Description:
Rabbit IgG polyclonal antibody for Mesothelin (MSLN) detection. Tested with WB, IHC-P, ELISA in Human.

Synonyms:
CAK 1 antibody, CAK1 antibody, CAK1 antigen antibody, cleaved form antibody, Megakaryocyte potentiating factor antibody, Mesothelin antibody, Mesothelin isoform 1 precursor antibody, MPF antibody, Msln antibody, MSLN_HUMAN antibody, Pre pro megakaryocyte potentiating factor antibody, Pre-pro-megakaryocyte-potentiating factor antibody, SMR antibody, SMRP antibody, Soluble MPF mesothelin related protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Mesothelin recombinant protein (Position: K306-L576). Human Mesothelin shares 57% and 56% amino acid (aa) sequence identity with mouse and rat Mesothelin, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.