Mesothelin polyclonal, anti-human, mouse, chicken, monkey

Protein Family: Cell Adhesion Molecules

Pathway and Disease: Cancers, Immune System, Signaling Molecules and Interaction

Description:
Mesothelin, also called megakaryocyte-potentiating factor (MPF), potentiates megakaryocyte colony formation in vitro. Membrane-anchored forms are involved in cellular adhesion. Antibodies against mesothelin are detected in patients with mesothelioma and ovarian cancer.

Alternate Names: Mesothelin, Pre-pro-megakaryocyte-potentiating factor, CAK1 antigen, MPF, MSLN

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500; IF: 1:100-1:500

Accession No.: Q13421

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human mesothelin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Dixit R et al. 2013. Development. 140 (21): 4398-406. PMID #24130328.
[2] Rinkevich Y et al. 2012. Nat Cell Biol. 14(12): 1251-1260. PMID #23143399.