METAP2 Antibody (N-term) Blocking Peptide

Background:
This gene is a member of the methionyl aminopeptidasefamily and encodes a protein that binds 2 cobalt or manganese ions.This protein functions both by protecting the alpha subunit ofeukaryotic initiation factor 2 from inhibitory phosphorylation andby removing the amino-terminal methionine residue from nascentprotein. Increased expression of this gene is associated withvarious forms of cancer and the anti-cancer drugs fumagillin andovalicin inhibit the protein by irreversibly binding to its activesite. A pseudogene of this gene is located on chromosome 2.

Other Names:
Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MetAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, 341118 {ECO:0000255|HAMAP-Rule:MF_03175}, Initiation factor 2-associated 67 kDa glycoprotein {ECO:0000255|HAMAP-Rule:MF_03175}, p67 {ECO:0000255|HAMAP-Rule:MF_03175}, p67eIF2 {ECO:0000255|HAMAP-Rule:MF_03175}, Peptidase M {ECO:0000255|HAMAP-Rule:MF_03175}, METAP2 {ECO:0000255|HAMAP-Rule:MF_03175}

Gene Name: METAP2 {ECO:0000255|HAMAP-Rule:MF_03175}

Gene ID: 10988
Primary Accession: P50579
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.