MFN1 Polyclonal Antibody

Background:
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks

Research Area: Cancer, Metabolism, Neuroscience, Signal Transduction, Tags and Cell Markers

Synonyms:
Fzo homolog, Hfzo1, Hfzo2, MFN 1, Mfn1, MFN1, Mitochondrial transmembrane GTPase Fzo 1, Mitochondrial transmembrane GTPase FZO 2, Mitochondrial transmembrane GTPase FZO1B, Mitofusin 1, Mitofusin-1, Mitofusin1, MS996, Putative transmembrane GTPase, Transmembrane GTPase MFN1

Immunogen: Recombinant protein of human MFN1

Swissprot: Q8IWA4
Gene Accession: BC040557

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-30363/sc-50330