MFN2 Antibody (Center) Blocking Peptide

MFN2 Antibody (Center) Blocking Peptide

€363.00
In stock
SKU
AC-BP8840c
Catalog Number: AC-BP8840c
Size: 500 µg
Datasheet
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Background:
MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.

Other Names:
Mitofusin-2, 365-, Transmembrane GTPase MFN2, MFN2, CPRP1, KIAA0214

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8840c was selected from the Center region of human MFN2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: MFN2 {ECO:0000303|PubMed:12598526, ECO:0000312|HGNC:HGNC:16877}

Gene ID: 9927
Primary Accession: O95140
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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