MFN2 antibody (clone 4H8), anti-human, rat
€435.00
In stock
SKU
AC-AT2852a
Catalog Number: AC-AT2852a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, Ehttps://www.abcepta.com/products/pdf_download/AT2852a-MFN2-Antibody-monoclonal-M03">Request Information AC-AT2852a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, Ehttps://www.abcepta.com/products/pdf_download/AT2852a-MFN2-Antibody-monoclonal-M03">Request Information AC-AT2852a">Request Information
Background:
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Other Names:
Mitofusin-2, 365-, Transmembrane GTPase MFN2, MFN2, CPRP1, KIAA0214
Antigen Type:
Recombinant Protein
Gene Name: MFN2 {ECO:0000303|PubMed:12598526, ECO:0000312|HGNC:HGNC:16877}
Gene ID: 9927
NCBI Accession: NP_001121132.1;NP_055689.1
Primary Accession: O95140
Other Accession: NM_014874
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Other Names:
Mitofusin-2, 365-, Transmembrane GTPase MFN2, MFN2, CPRP1, KIAA0214
Antigen Type:
Recombinant Protein
Gene Name: MFN2 {ECO:0000303|PubMed:12598526, ECO:0000312|HGNC:HGNC:16877}
Gene ID: 9927
NCBI Accession: NP_001121132.1;NP_055689.1
Primary Accession: O95140
Other Accession: NM_014874
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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