Mfn2 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71425
Background:
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Alternative Name:
HSG, MARF, CMT2A, CPRP1, CMT2A2,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: Mfn2 polyclonal antibody detects endogenous levels of Mfn2 protein.
Immunogen:
Recombinant protein of human MFN2.
MW: ~ 86 kDa
Swis Prot.: O95140
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Alternative Name:
HSG, MARF, CMT2A, CPRP1, CMT2A2,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: Mfn2 polyclonal antibody detects endogenous levels of Mfn2 protein.
Immunogen:
Recombinant protein of human MFN2.
MW: ~ 86 kDa
Swis Prot.: O95140
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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