Mfn2 Polyclonal Antibody

Background:
mitofusin 2(MFN2) Homo sapiens This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],

Alternative Names:
MFN2, CPRP1, KIAA0214, Mitofusin-2, Transmembrane GTPase MFN2

Immunogen: The antiserum was produced against synthesized peptide derived from human Mfn2. AA range:354-403

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 86

GeneID: MFN2

Storage: -20°C/1 year

NOTE: For Research Use Only