MFN2 polyclonal (Center), anti-human, mouse

MFN2 polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP8840c
Catalog Number: AC-AP8840c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21136
Applications: WB, FC, IHC-P
Datasheet

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Background:
MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.

Other Names:
Mitofusin-2, 365-, Transmembrane GTPase MFN2, MFN2, CPRP1, KIAA0214

Target/Specificity:
This MFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 447-476 amino acids from the Central region of human MFN2.

Antigen Region:
447-476

Antigen Type: Synthetic Peptide

Gene Name: MFN2 {ECO:0000303|PubMed:12598526, ECO:0000312|HGNC:HGNC:16877}
Gene ID: 9927
Primary Accession: O95140
NCBI Accession: NP_001121132.1;NP_055689.1
Other Accession: Q8R500; Q80U63
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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