MFNG antibody (clone 2B11), anti-human
€435.00
In stock
SKU
AC-AT2853a
Catalog Number: AC-AT2853a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT2853a">Request Information
Background:
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
Other Names:
Beta-1,3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, MFNG
Antigen Type:
Recombinant Protein
Gene Name: MFNG (HGNC:7038)
Gene ID: 4242
NCBI Accession: NP_001159815.1;NP_002396.2
Primary Accession: O00587
Other Accession: NM_002405
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
Other Names:
Beta-1,3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, MFNG
Antigen Type:
Recombinant Protein
Gene Name: MFNG (HGNC:7038)
Gene ID: 4242
NCBI Accession: NP_001159815.1;NP_002396.2
Primary Accession: O00587
Other Accession: NM_002405
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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