MGLL Polyclonal Antibody

Background:
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction

Synonyms:
EC 3.1.1.23, HU K5, HU-K5, HUK5, Lysophospholipase homolog, Lysophospholipase like, Lysophospholipase-like, MAGL, MGL, MGLL, MGLL, Monoacylglycerol lipase, Monoglyceride lipase

Immunogen: Synthetic peptide of human MGLL

Swissprot: Q99685
Gene Accession: NP_001003794

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-54110/sc-54111/sc-134789