mGluR1 polyclonal, anti-human, mouse, rat

Background:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

Alternative Name:
mGluR1, GRM1, Glutamate receptor metabotropic 1, glutamate receptor, metabotropic 1, GPRC1A, GRM1, GRM1-Alpha, GRM1, GRM1A, Metabotropic glutamate receptor 1, mGlu1, mGluR1, MGLUR1-Alpha, MGLUR1A, SCAR13,

Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200

Specificity: mGluR1 polyclonal antibody detects endogenous levels of mGluR1 protein.

Immunogen:
recombinant protein

MW: 200 kDa

Swiss-Prot: Q13255(Human) P97772(Mouse) P23385(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.