mGluR1 polyclonal, anti-rat

Protein Family: Receptors and Channels

Pathway and Disease: Nervous and Sensory Systems, Neurodegenerative Disorders, Cell Communication, Signaling Molecules and Interaction, Signal Transduction

Description:
Metabotropic glutamate receptor 1 (mGluR1) is a receptor for glutamate. The activity of mGluR1 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. mGluR1 participates in the cental action of glutamate in the CNS such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.

Alternate Names: Metabotropic glutamate receptor 1, mGluR1, Grm1, Gprc1a, Mglur1

Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:500

Accession No.: P23385

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat mGluR1a.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.