mGluR2 polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Nervous and Sensory Systems, Cell Communication, Signaling Molecules and Interaction

Description:
Metabotropic glutamate receptor 2 (mGluR2) is a receptor for glutamate. The activity of mGluR2 is mediated by a G-protein that inhibits adenylate cyclase activity. mGluR2 mediates suppression of neurotransmission and is involved in synaptogenesis or synaptic stabilization.

Alternate Names: GRM2, Metabotropic glutamate receptor 2, mGluR2, GPRC1B, MGLUR2 

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q14416

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human mGluR2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Guntert T et al. 2016. Neuropharmacology. 110(Pt A): 211-222. PMID 27016021.