MGMT monoclonal, anti-human
€0.00
In stock
SKU
AC-AM2217b
Catalog Number: AC-AM2217b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 888CT22.2.4
Applications: IHC-P, IF, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 888CT22.2.4
Applications: IHC-P, IF, WB
Datasheet
Request Information
Background:
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Other Names:
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT
Target/Specificity:
Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: MGMT
Gene ID: 4255
Primary Accession: P16455
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Other Names:
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase, MGMT
Target/Specificity:
Purified His-tagged MGMT protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: MGMT
Gene ID: 4255
Primary Accession: P16455
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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