MHC II DQ (clone EBS-O-114), anti-human, pig

Source:
A BALB/c mouse was immunized with cells of T4+ CTL clone HG-38.
Fusion partner: Sp2/0.

Specifications:
EBS-O-114 reacts with HLA Class II. The antibody was shown to strongly block cytotoxic activity of T4+ cytotoxic T cell clones. Distribution studies on cell lines suggested that EBS-O-114 is directed against a DQ rather than a DR antigen.

Species reactivity:
Positive: human, pig.

Applications:
Demonstration of MHC II DQ.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Immunoprecipitation: +
Paraffin sections: +

Positive control: Raji cells. Tonsil or lymph node.

References:
- Spits H, et al, Hybridoma2: 423-437 (1983).
- Spits H, et al,Eur. J. Immunol.14, (1984).
- Bontrop R, et al,Tissue Antigens, 27, (1986)